Advantages of the TFF Filtration System

Hanbon's Bio-TFF Tangential Flow Filtration System has gained widespread recognition in the fields of biopharmaceuticals, vaccines, pilot scale, and small-scale production due to its exceptional performance and outstanding engineering design. Based on advanced membrane separation technology, the tangential flow filtration tff system efficiently performs critical process steps such as concentration, buffer exchange, and molecular weight cut-off. It has become an indispensable piece of equipment in modern bioprocessing.

Protecting Biologically Active Molecules

Unlike traditional forward filtration, the TFF filtration system uses tangential flow, where the liquid flows parallel to the membrane surface. This method effectively reduces membrane fouling and increases both flux and filtration efficiency. The system is equipped with sanitary-grade diaphragm or rotor pumps, which provide low shear and low-pulse fluid delivery. This is especially crucial when processing sensitive biological molecules such as proteins, peptides, or viruses, as it significantly reduces the risk of product denaturation.

Intelligent Control

In terms of automation, the TFF tangential flow filtration system is equipped with a highly integrated automatic transmembrane pressure (TMP) control module. This module ensures that operations like concentration and diafiltration are performed with precision, based on the set parameters, thereby guaranteeing process consistency and reproducibility.

Seamless Transition from Lab to Large-Scale Production

The TFF filtration system offers a wide range of membrane area options, making it suitable for various settings, from laboratory and pilot scale to commercial production. Additionally, the system offers a rich array of configuration options, allowing users to customize the piping, pump type, control system, and membrane material according to specific process needs. This greatly enhances the system's versatility and scalability.

Overall, Hanbon's TFF filtration system stands out as a leader in high-end filtration equipment, offering multiple advantages, including high efficiency, safety, flexibility, and compliance with regulatory standards. It is particularly suitable for pharmaceutical companies with high standards and stringent requirements, especially in concentration and purification processes.