English 
CN
Bio-TFF tangential flow filtration system is an easy-to-use automatic ultrafiltration UF/DF system suitable for biopharmaceutical process development, pilot studies, and small-scale production. The Bio TFF system adopts innovative and intelligent design, which not only improves process performance, but also achieves extremely low minimum operating volume, maximum ultrafiltration concentration multiple, and optimal product recovery function.
Hygienic design, compliant with GMP and ASME BPE requirements;
Use sanitary grade quaternary diaphragm pump or rotor pump, low shear force, low pulse;
Automatic TMP control, automatic concentration, equal volume filtration and other functions;
Equipped with a built-in integrity detection module, without the need for an external integrity detector;
Chinese and English operating system complies with the requirements of FDA 21 CFR Part 11;
Customization can be customized according to different customer requirements;
Provide a complete set of GMP verification documents and services.
| Model No. | Bio-TFF 1200 | Bio-TFF 2500 | Bio-TFF 5t | Bio-TFF 8t | Bio-TFF 10t | Bio-TFF 20t | Bio-TFF 30t | Bio-TFF 50t | Bio-TFF 60t |
| Working flowL/h | 150 -1000 | 600 -2000 | 900 -4000 | 1500 -6000 | 3000 -8000 | 8000 -16000 | 8000 -30000 | 20000 -50000 | 20000 -60000 |
| Adaptation area m2 | 0.5~3 | 2~5 | 3~10 | 5~15 | 10~20 | 20~40 | 40~80 | 80~120 | 80~160 |
| Pipe Size（ inch） | 3/4" | 1" | 1.5" | 1.5"or2" | 2" | 2.5" | 3"or4" | 4" | 4"or6" |
| pH range | 0~14 | ||||||||
| Conductivity range（mS/cm） | 0.1uS/cm~300mS/cm | ||||||||
| Pipe materia | SS316L(ASME BPE), Electric projectile Ra≦0.4µm | ||||||||
| Solvent mixing tank（L） | Optional (20/30/50/100 and others) | ||||||||
| Fluid replenishment pump | Optional | ||||||||
| System pressure（bar） | ≤6 | ||||||||
| Power | 220/380VAC 50Hz | ||||||||
| Compressed air（bar） | 5~7 | ||||||||
Note:
The company can also provide the Bio-HF ultrafiltration system adapted to the hollow fiber column. This configuration parameter table is also suitable for the hollow fiber ultrafiltration system .
The above are standard models. The system configuration can be customized according to the actual process .
The above parameters are for reference only. The final configuration parameters shall be subject to the DQ file.
