Bio-Lab laboratory chromatography system is a highly efficient, fast, and reliable automatic chromatography device independently developed by Hanbon, which can be used for the rapid purification of biological molecules such as protein, polypeptide, and nucleic acids from micrograms to grams. The system uses modular design and intelligent software, combined with different specifications of chromatographic columns, to meet the purification requirements of various biological macromolecules in the laboratory.
High performance system pumps, detectors, mixers, and various control valves provide good accuracy and repeatability, ensuring that expected results can be obtained quickly;
Modular design facilitates system maintenance, and combined with powerful system software, it can achieve flexible configuration upgrades to meet the multi user login mode;
Stacked pipeline design, small dead volume of pipeline, good biocompatibility of all pipelines and components in contact with the sample, and full protection of protein activity;
The software complies with GLP/GMP regulations and FDA 21 CFR Part 11 requirements;
The software features complete functionality, a good user experience, and a switchable interface in both Chinese and English to meet multi-level user permissions and complete audit tracking requirements.
Series configuration
| Model | Bio-Lab 30 | Bio-Lab 100 | Bio-Lab 150 | Bio-Lab 300 | |
Mobile phase selection module | Inlet valve | 2 Channels | 2 Channels | 2 Channels | 4 Channels |
| Infusion module | Infusion pump | PEEK pump, made of bioinert material, features self-flushing of the pump head and can provide excellent gradient accuracy and repeatability | |||
| Flow velocity range | 0-30mL/min | 0-100mL/min | 0-150mL/min | 0-300mL/min | |
| Flow accuracy | ±1% | ±1% | ±1% | ±1% | |
| Gradient type | socratic, linear, and the gradient ratio can be modified online | ||||
| Mixer | 0.5/2mL | 0.5/2mL | 0.5/2mL | 5mL | |
| Injection module | Injection Valves | Automatic injection, software-controlled switching of Load, Inject and Waste functions, capable of quantitative loop injection | |||
| Separation module | Column position valve | Supports forward/reverse flushing and Bypass functions | |||
| Detection module | UV Detector | Simultaneously detect any two wavelengths within the range of 190-400nm, with wavelength accuracy and repeatability: ±1nm | |||
| Electrical conductivity detector | Detection range: 0.001-999.99mS/cm, accuracy ±2%, equipped with a temperature sensor | ||||
| pH Detector | Detection range: pH 0-14, accuracy ± 0.05 | ||||
| Temperature sensor | Integrated on the conductivity detector, it can perform temperature compensation for pH and conductivity | ||||
| Data processing module | Chromatographic workstation | Pre-install the chromatography workstation | |||
| Computer | All-in-one computer, CPU≥I5, memory ≥8G, hard disk ≥1T | ||||
| System accessories | Back pressure valve (pressure limiter) | Provide a certain back pressure to the system | |||
| Toolkit | Including PEEK/PTFE tubing, installation manual, user manual, tubing joints, commonly used tools, etc | ||||
| System external dimensions | Power | 1500W | 1500W | 1500W | 2000W |
| Dimensions(mm) | 450×585×604 | 450×585×604 | 450×585×604 | 616×544×673 | |
Bio-Lab600/1000 Configuration List
| Model | Bio-Lab 600 | Bio-Lab 1000 | |
| Infusion pump | A//B pump Velocity range:4-600ml/min(Double pump superimposed column mode1‒1200ml/min) Velocity accuracy:±1.5% Scope of use:5%-95% Pressure range:0‒2MPa (20bar,290 psi) | A//B pump Velocity range:6-1000ml/min (Double pump superimposed column mode12‒2000ml/min) Velocity accuracy:±1.5% Scopeof use:5%-95% Pressure range:0‒1.5MPa (15bar,218 psi) | |
| AB pump inlet | Single pump 4 inlet; Double pumps total 8 intakes | ||
| Bubble sensor | A maximum of three files are supported | ||
| Pressure sensor | A, B pump after each one, one in front of the column, one after the column, a total of four, the detection range of 0-2MPa | ||
| Bubble trap | Effective removal of bubbles from the system, optional online or offline; Bubble trap volume: 120ml | ||
| Mixer | Mixing chamber volume: 10ml | ||
| Column valve | Single column | ||
| UV detector | 190-400nm, dual wavelength detection, wavelength accuracy ±1nm | ||
| pH detector | Detection range: 2-12, accuracy ±0.1 | ||
| Conductance detector | Detection range: 0.1-999.9mS /cm; Flow pool volume: Accuracy: ±3%, built-in temperature sensor, automatic conductance temperature compensation | ||
| Outlet valve | ≥4 exits | ||